BS Medicine Podcast

Hosted by James McCormack and Mike Allan .

These podcasts promote healthy skepticism and critical thinking, with the majority presented in a case-based format.

Recommended Listening

Episode 436: Hydrochlorothiazide and squamous cell skin cancer – what we know

In episode 436, Mike and James invite Samantha Moe to help us work through the recent evidence suggesting that hydrocholorothiazide is associated with squamous cell skin cancer. We go over all the numbers and talk about how we use cohort data to figure out if an association needs to influence our clinical practice. As always it is tricky. Show notes...

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Episode 435: Unwrapping the subclinical hypothyroidism enigma

In episode 435, Mike and James unravel the evidence around thyroid testing. We talk about an approach to deal with the lack of research and the variation in the measurement of TSH and many other things. At the end we both complain of fatigue, dry skin, puffy eyes, anxiety and depression – and immediately get a TSH test. Show notes 1) Tools for Practice...

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Episode 433: Yes, more diabetes trials

In episode 433, Mike and James get all sweet on the latest diabetic trials from 2019. We provide the results, the critique and the context and we do it all with our usual level of charm and wit – which is by all accounts at a level similar to the size of the effect that many diabetes medications have on CVD events.  Show notes...

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Episode 432: All the evidence for all the medications for a failing heart – PART III

In episode 432, James and Mike finish their review of the evidence around medications for systolic heart failure. In this episode our goal was to try to make sense of the process by adding as much art as possible to the evidence and also use a modicum of common sense. Let us know if we achieved our goal. Show notes...

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Episode 431: All the evidence for all the medications for a failing heart – PART II

In episode 431, James and Mike continue their review of the evidence around medications for systolic heart failure. In this episode we discuss betablockers, ACEIs, ARBs, MRAs and a few other key trials of somewhat newer agents.  Show notes Podcast handout ...

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Episode 430: All the evidence for all the medications for a failing heart

In episode 430, James and Mike do a review of all the best available evidence around medications for systolic heart failure. In this episode we start off by framing the risk associated with heart failure (mortality and hospitalizations for heart failure) and what the evidence is for exercise, salt, diuretics, digoxin and ISDN/hydralazine. Show notes...

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