BS Medicine Podcast

Hosted by James McCormack and Mike Allan .

These podcasts promote healthy skepticism and critical thinking, with the majority presented in a case-based format.

Recommended Listening

Episode 483: Aducanumab for Alzheimer’s – forget about it?

In episode 483, James and Mike invite Tina to the podcast to talk about the aducanumab (Aduhelm) FDA approval story. We look at all the latest evidence, we talk about how people analyzed the data, whether or not the findings were clinically important, the side effects and finally the cost. And no matter how we looked at it we were still puzzled it got FDA approval. What do you think?...


Episode 482: A deep dive into baths for atopic dermatitis

In episode 482, Mike and James take a look into all the evidence for baths for atopic dermatitis. The evidence is fairly clear that more frequent bathing has a reasonable effect in people with moderate to severe atopic dermatitis. However, adding bleach or anything else to the bath doesn’t seem to do much at all. Show notes Coming soon ...


Episode 481: Clearing up the evidence for topical acne combination products

In episode 481, James and Mike invite Paul Fritsch to go through all the evidence for the benzoyl peroxide/adapalene and benzoyl peroxide/clindamycin combinations that we use for acne. Call us crazy, but we focus on the important outcome of whether or not the patient thinks the treatment worked....


Episode 480: Reducing risk rather than reducing surrogates

In episode 480, James and Mike talk about two recent meta-analyses that have done a solid job of looking at the impact of lowering blood pressure and using SGLT-2s and GLP-1s to reduce risk. Both publications lend credence to the concept of focusing much more on risk reduction goals than blood pressure or glucose thresholds. Show notes...


Episode 479: Cannabinoids – an update (not much) for chronic pain

In episode 479, Mike and James update the latest information around cannabinoids for chronic pain. Unfortunately, there is not a lot of new information but we talk about what there is and then try and put all the evidence into context and then how to think about the information we have. Show notes...


Episode 478: How to slow the flow: NSAIDs for heavy menstrual bleeding

In episode 478, James and Mike invite Jen Potter to the podcast yet again to talk about whether or not NSAIDs are effective for reducing menstrual bleeding. While the quality of the evidence is not great, there does appear to be some evidence that NSAIDs have an effect over placebo. Show notes Tools for Practice...